top of page

Peer Reviewed Publications

2023

» Thenin-Houssier, S., S. Machida, C. Jahan, J. Bonnet-Madin, S. Abbou, H.-C. Chen, R. Tesfaye, O. Cuvier, and M. Benkirane. POLE3 is a transcriptional repressor of unintegrated linear HIV-1 DNA required for efficient virus integration and escape from innate immune sensing. Sci. Adv. DOI:10.1126/sciadv.adh3642.

» Więcek, K., and Chen, H.-C. Understanding latent HIV-1 reservoirs through host genomics approaches. iScience DOI:10.1016/j.isci.2023.108342.

» Chen, H.-C. A systematic review of the barcoding strategy that contributes to COVID-19 diagnostics at a population level. Front. Mol. Biosci. DOI:10.3389/fmolb.2023.1141534.

» Chen, H.-C. The Dynamic Linkage between Provirus Integration Sites and the Host Functional Genome Property Alongside HIV-1 Infections Associated with Antiretroviral Therapy. Vaccines. DOI: 10.3390/vaccines11020402.

» Thenin-Houssier, S., S. Machida, C. Jahan, J. Bonnet-Madin, S. Abbou, H.-C. Chen, R. Tesfaye, O. Cuvier, and M. Benkirane. POLE3 is a transcriptional repressor of unintegrated linear HIV-1 DNA required for efficient virus integration and escape from innate immune sensing. ResearchSquare DOI: 10.21203/rs.3.rs-2429067/v1.

2022

» Chen, H.-C. The dynamic linkage between intact provirus integration sites and the host functional genome property alongside HIV-1 infections associated with antiretroviral therapy. BioRxiv. DOI: 10.1101/2022.12.02.518849.

» Chen, H.-C. 2022. Use molecular barcodes to study emerging infectious diseases. AUTHOREA doi.org/10.22541/au.165285401.15076943/v1

» Chen, H.-C. 2022. Position matters - a discussion of HIV gene expression (中文主題名稱:原來擺對位置很重要 — 淺談人類免疫缺陷病毒的基因表現). Science Education Monthly (科學教育月刊). ISSN 1021-3708  ISSN 1021-3708, 454, P25-32, DOI:10.6216/SEM

2021

» Lucic, B.*, H.-C. Chen*, M. Kuzman*, E. Zorita*, J. Wegner, V. Minneker, W. Wang, R. Fronza, M. Schmidt, and R. Stadhouders, V. Roukos, K. Vlahovicek, G. Filion and M. Lusic. 2019. Author Correction: Spatially clustered loci with multiple enhancers are frequent targets of HIV-1. Nat. Communications. doi.org/10.1038/s41467-021-26471-w (*Shared first authors

2020

» Vansant*, G., H.-C. Chen*, E. Zorita, Trejbalová, K., Miklík, D., G. Filion, and Z. Debyser. 2020. The chromatin landscape at the HIV-1 provirus integration site determines viral expression. Nucleic Acids Research. doi.org/10.1093/nar/gkaa536 (*Shared first authors) (Q1; IF: 11.147)

» Machida, S., D. Depierre, H.-C. Chen, S. Houssier, G. Petitjean, C. Doyen, M. Takaku, O. Cuvier and M. Benkirane. 2020. Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome. PNAS. doi: 10.1073/pnas.1913754117 (Q1; IF: 9.58)

2019

» Lucic, B.*, H.-C. Chen*, M. Kuzman*, E. Zorita*, J. Wegner, V. Minneker, W. Wang, R. Fronza, M. Schmidt, and R. Stadhouders, V. Roukos, K. Vlahovicek, G. Filion and M. Lusic. 2019. Spatially clustered loci with multiple enhancers are frequent targets of HIV-1. Nat. Communications. doi: 10.1038/s41467-019-12046-3 (*Shared first authors) (Q1; IF: 11.878; citation: 3)

2018

» Abner, E., M. Stoszko, L. Zeng, H.-C. Chen, A. Izquierdo-Bouldstridge, T. Konuma, E. Zorita, E. Fanunza, Q. Zhang, T. Mahmoudi, M.-M. Zhou, G. Filion, and A. Jordan. 2018. A new quinoline BRD4 inhibitor targets a distinct latent HIV-1 reservoir for re-activation from other ‘shock’ drugs. J Virol. doi: 10.1128/JVI.02056-17. (Q1; IF: 4.324; citation: 10)

» Chen, H.-C.*, E. Zorita, and G. Filion*. 2018. Using Barcoded HIV Ensembles (B-HIVE) for single provirus transcriptomics. Curr Protoc Mol Biol. doi: 10.1002/cpmb.56 (*Corresponding authorship) (Q1; citation: 3)

» Lucic, B.*, H.-C. Chen*, M. Kuzman*, E. Zorita*, J. Wegner, V. Minneker, V. Roukos, W. Wang, R. Fronza, M. Schmidt, M. Benkirane, R. Stadhouders, K. Vlahovicek, G. Filion and M. Lusic. 2018. Spatially clustered loci with multiple enhancers are frequent targets of HIV-1. 2018. Spatially clustered loci with multiple enhancers are frequent targets of HIV-1. BioRxiv. doi: https://doi.org/10.1101/287896. (*Shared first authors)

2017

» Chen, H.-C., J.P. Martinez, E. Zorita, A. Meyerhans, and G. Filion. 2017. Position effects influence HIV latency reversal. Nat Struct Mol Biol. doi: 10.1038/nsmb.3328. (Q1; IF: 12.109; citation: 56)

2015

» Corrales, M., P. Cusco, D.R. Usmanova, H.-C. Chen, N.S. Bogatyreva, G.J. Filion, and D.N. Ivankov. 2015. Machine learning: how much does it tell about protein folding rates? PLoS One. doi:10:e0143166. (Q1; IF: 2.776; citation: 12)

2008

» Chen, P.M., H.-C. Chen, C.T. Ho, C.J. Jung, H.T. Lien, J.Y. Chen, and J.S. Chia. 2008. The two-component system ScnRK of Streptococcus mutans affects hydrogen peroxide resistance and murine macrophage killing. Microbes and Infection. doi:10:293-301. (Q2; IF: 2.669; citation: 32)

Publications

Natural Products Report inside frint cover                                                                                                                                     Vol. 32, No. 1, January, 2015

Peripheral ARTeries – Personal interview & featured artworks                                                                                                               The March issue, 2014

                     Official link: http://issuu.com/artpress/docs/peripheral_arteries_art_review_-_ma

                     Direct link: http://issuu.com/artpress/docs/peripheral_arteries_art_review_-_ma/26 

Molecular Cell cover image                                                                                                                                                                              Vol. 52, issue 5, 2013 

Scientific Image | Imatge científica - HIV Infection | Infecció per VIH                                                                                                 El-lipse, NÙM. 66, 2013

                                                                                                                                                                   (Parc Recerca Biomèdica Barcelona monthly newspaper)

Image Credits

Image credit: “MRN: un maillon dans la chaine de protection du génome”, Institut des sciences biologiques          (INSB) CNRS web site sketch, May, 2021

iCLIP: Genomic views of protein-RNA interactions                                                                                                                                   EMBO Practical Course, 2013

Acknowledgements

Martinez, J.P., F. Sasse, M. Brönstrup, J. Diez and A. Meyerhans. 2015. Antiviral drug discovery: broad-spectrum drugs from nature. Nat. Prod. Rep. (DOI: 10.1039/C4NP00085D)

 

Public Media

LA VANGUARDIA                        El virus del sida se esconde en el genoma de las células   22-NOV-2016

 

EurekAlert!                                 Stop playing seek-and-hide with latent HIV   23-NOV-2016 

 

AlphaGalileo                              Stop playing seek-and-hide with latent HIV   23-NOV-2016

 

The Medical News                    Scientists develop new technology that sheds light on HIV infection   23-NOV-2016

 

Infection Control Today          Researchers Develop New Technology to Detect Latent HIV   23-NOV-2016

 

Health Medicine Network     A new tool to find latent HIV will advance the current treatment strategies   23-NOV-2016

 

MedicalXpress                           A new tool to find latent HIV will advance the current treatment strategies   23-NOV-2016

 

Physician's Weekly                  Stop Playing Seek-and-Hide With Latent HIV   28-NOV-2016

 

Press

Molecular Cell cover image

( Vol. 52, issue 5, 2013)

Poster Design: COURSES@CRG series 2015: #1 Exome sequencing

Poster Design: COURSES@CRG: Somatic cell programming

Poster Design: COURSES@CRG series 2015: #6 iPS cells

Nature Prodcut Reports inside front cover & Graphical abstract (Vol. 32, No. 1, January, 2015)

Poster Design: COURSES@CRG series 2015: #3 Advanced Proteomics

Poster Design: V CRG postdoctoral symposium

Poster Design: COURSES@CRG series 2015: #7 Genome Editing Tools

EMBO Practical Course: iCLIP (15-21 Nov. 2015, Mainz, Germany)

Poster Design: COURSES@CRG series 2015: #4 Introduction of C. elegans

Poster Design: CONFERENCE@Middle East Technical University, Ankara, Turkey: Aykut KENCE evolution conferenc

Poster Design: COURSES@CRG series 2015: #0 Carnivalesque

Poster Design: COURSES@CRG series 2015: #5 Chromosomal Confirmation

Poster Design: COURSES@CRG: Genome wide approaches to study functional protein/RNA interactions

Poster Design: COURSES@CRG series 2016: #1 Whole-Cell Modeling

bottom of page